| 货号 | 3568/10 |
| 别名 | 13-[(2,6-Dideoxy-3-C-methyl-3-O-met |
| 供应商 | Tocris |
| 生物活性 | Macrolide antibiotic. Inhibits 50S ribosomal subunit formation and elongation at transpeptidation step in gram-positive and gram-negative organisms. Orally active with improved pharmacokinetics over erythromycin in mouse models. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 纯度 | >99 % |
| 计算分子量 | 748.98 |
| 分子式 | C19H20BrN3O3 |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO and to 100 mM in ethanol |
| CAS号 | 84379-13-5 |
| 参考文献 | Champney and Burdine (1995) Macrolide antibiotics inhibit 50S ribosomal subunit assembly in Bacillus subtilisandStaphylococcus aureas. Antimicrob.Agents Chemother. 39 2141. PMID: 8540733. Girardet al (1987) Pharmacokinetic and in vivo studies with azithromycin (CP-62,993), a new macrolide with extended half-life and excellent tissue distribution. Antimicrob.Agents Chemother. 31 1948. PMID: 2830841. Retsemaet al (1987) Spectrum and mode of action of azithromycin (CP-62,993), a new 15-membered-ring macrolide with improved potency against gram-negative organisms. Antimicrob.Agents Chemother. 31 1939. PMID: 2449865. |