Iberiotoxin
货号：
14608-100ug 基本售价：
2450.0 元 规格：
100 ug
产品信息
概述| 货号 | 14608-100ug |
| 描述 | Iberiotoxin, a peptide purified from venom of the scorpion B. tamulus, is a selective blocker of large-conductance calcium ion-activated potassium ion channels (BKCa). In single channel recordings, iberiotoxin can reversibly block outward currents mediated by BKCa in excised membrane patches from bovine aortic smooth muscle with an IC50 value of 250 pM.1 It is also a noncompetitive, partial inhibitor of charybdotoxin binding in bovine aortic sarcolemmal membrane vesicles (Ki = 250 pM).1 |
性能| 供应商 | Cayman |
| 应用文献 |
1.Galvez, A.,Gimenez-Gallego, G.,Reuben, J.P., et al. Purification and characterization of a unique, potent, peptidyl probe for the high conductance calcium-activated potassium channel from venom of the scorpion Buthus tamulus. The Journal of Biological Chemisty 265(19), 11083-11090 (1990).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥95% |
| 计算分子量 | 4230.9 |
| CAS号 | 129203-60-7 |
| 稳定性 | ≥ 6 months |
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