货号 | 1652-10 |
描述 | A potent SIRT1 inhibitor (IC₅₀ = 38 nM). EX-527 is 200-500-fold more selective for SIRT1 than for SIRT2 or SIRT3. Does not inhibit SIRT4-7, does not inhibit class I/II HDAC activity at concentrations up to 100µM. Enhances p53 acetylation in response to DNA damaging agents. |
供应商 | Biovision |
运输条件 | Blue Ice |
存放说明 | +4℃ |
外观 | White solid |