| 货号 | 6011/100U |
| 供应商 | Tocris |
| 生物活性 | TLR2/6 agonist (also a putative TLR10 ligand). Activates NF-κB. Induces pro-inflammatory cytokines including IL-8, IL-1β, CCL20 and TNF-αin vitro. Synergizes with IFNγ to induce CXCL10 release from melanoma cells. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 计算分子量 | 1666.16 |
| 分子式 | C84H140N14O1 |
| 可溶性/溶解性 | Soluble to 2 mg/ml in water |
| 序列号 | CGDPKHPKSF (Modifications: Cys = S-[2,3-Bis(palmitoyloxy)-(2-R/ |
| 参考文献 | Leet al (2016) Stable toll-like receptor 10 knockdown in THP-1 cells reduces TLR-ligand-induced proinflammatory cytokine expression. Int.J.Mol.Sci. 17 E859. PMID: 27258267. Mauldinet al (2015) TLR2/6 agonists and interferon-gamma induce human melanoma cells to produce CXCL10. Int.J.Cancer 137 1386. PMID: 25765738. Okusawaet al (2004) Relationship between structures and biological activities of mycoplasmal diacylated lipopeptides and their recognition by toll-like receptors 2 and 6. Infect.Immun. 72 1657. PMID: 14977973. |