货号 | 3787/10 |
别名 | (S)-3,6-Diamino-N-((3S,9S,12S,15S,Z |
供应商 | Tocris |
生物活性 | Member of the tuberactinomycin family of antibiotics. Inhibits group I intron splicing and prokaryotic protein synthesis. Freezes bacterial ribosomes in either the pre- or post-translational state. Facilitates trans-cleavage of the Neurospora VS ribozyme. |
运输条件 | Blue Ice |
存放说明 | -20℃ |
计算分子量 | 881.85 |
分子式 | C25H43N13O10 |
可溶性/溶解性 | Soluble to 75 mM in water |
CAS号 | 32988-50-4 |
参考文献 | Ermolenkoet al (2007) The antibiotic viomycin traps the ribosome in an intermediate state of translocation. Nat.Struct.Mol.Biol. 14 493. PMID: 17515906. Schroederet al (2000) Modulation of RNA function by aminoglycoside antibiotics. EMBO J. 19 1. PMID: 10619838. Hausneret al (1988) The allosteric three-site model for the ribosomal elongation cycle. J.Biol.Chem. 263 13103. PMID: 2843509. |