| 货号 | 5677/1 |
| 供应商 | Tocris |
| 生物活性 | Potent endogenous NPFF receptor agonist (EC50 values are 0.0011 and 29 nM for NPFF2 and NPFF1, respectively). Attenuates contractile function of isolated rat and rabbit cardiac myocytes. Reduces heart rate, stroke volume, ejection fraction and cardiac output, and increases plasma prolactin levels in rats. GnIH homolog. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 计算分子量 | 1428.72 |
| 分子式 | C67H101N19O1 |
| 序列号 | MPHSFANLPLRF (Phe-12 = C-terminal amide) |
| 参考文献 | Nicholset al (2010) Human RFamide-related peptide-1 diminishes cellular and integrated cardiac contractile performance. Peptides 31 2067. PMID: 20797420. Gouardèreset al (2006) Functional differences between NPFF1 and NPFF2 receptor coupling: high intrinsic activities of RFamide-related peptides on stimulation of [35S]GTPγS binding. Neuropharmacology 52 376. PMID: 17011599. Hinumaet al (2000) New neuropeptides containing carboxy-terminal RFamide and their receptor in mammals. Nat.Cell.Biol. 2 703. PMID: 11025660. |