| 货号 | 0554/100 |
| 别名 | N-Methyl-β-carboline-3-carboxamide |
| 供应商 | Tocris |
| 生物活性 | Inverse agonist and anxiogenic agent. Increases tyrosine hydroxylation and causes upregulation of β-adrenoceptors in mouse cerebral cortex. |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 纯度 | >99 % |
| 计算分子量 | 225.25 |
| 分子式 | C13H11N3O |
| 可溶性/溶解性 | Soluble to 75 mM in 1eq. HCl and to 100 mM in DMSO |
| CAS号 | 78538-74-6 |
| 参考文献 | Donneret al (1989) Evidence for an excitatory action of benzodiazepine receptor inverse agonist FG 7142 on C-fibre afferents. Naunyn Schmiedebergs Arch.Pharmacol. 340 352. PMID: 2478895. Knorret al (1989) The anxiogenic β-carboline FG-7142 increases in vivoandin vitro tyrosine hydroxylation in the prefrontal cortex. Brain Res. 495 355. PMID: 2765936. Wettstei (1989) Behavioural studies with the β-carboline FG 7142 combined with related drugs in monkeys. Eur.J.Pharmacol. 163 219. PMID: 2498110. Stanfordet al (1987) A single dose of FG 7142 causes long term increases in mouse cortical β-adrenoceptors. Eur.J.Pharmacol. 134 313. PMID: 3032657. |