Ramelteon
货号：
20389-25mg 基本售价：
2366.0 元 规格：
25 mg
产品信息
概述| 货号 | 20389-25mg |
| 描述 | Ramelteon is an indane derivative of melatonin that displays high binding affinity at both melatonin receptors (Kis = 14 and 45 pM for MT1 and MT2, respectively).1 It does not show any appreciable binding to GABAA receptors and has not been shown to produce dependence nor potential for abuse in preclinical and clinical assessment of reinforcing effects.2 |
| 别名 | TAK-375; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Chan, K.H., and Wong, Y.H. A molecular and chemical perspective in defining melatonin receptor subtype selectivity. International Journal of Molecular Sciences 14(9), 18385-18406 (2013).
2.Griffiths, R.R., and Johnson, M.W. Relative abuse liability of hypnotic drugs: A conceptual framework and algorithm for differentiating among compounds. J. Clin. Psychiatry 66(Suppl 9), 31-41 (2005).
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| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 259.3 |
| 分子式 | C16H21NO2 |
| CAS号 | 196597-26-9 |
| 稳定性 | ≥ 2 years |
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