货号 | 3602/1 |
别名 | [(3R)-3-amino-4-[(3-hexylphenyl)ami |
供应商 | Tocris |
生物活性 | Potent sphingosine-1-phosphate receptor S1P1 selective antagonist (Ki = 18 nM); displays no effect at S1P2, S1P3 or S1P5. Enhances capillary leakage and restores lymphocyte egress in vivo. |
运输条件 | Blue Ice |
存放说明 | -20℃ |
纯度 | >98 % |
计算分子量 | 342.37 |
分子式 | C16H27N2O4 |
可溶性/溶解性 | Soluble to 20 mM in 1eq. NaOH |
参考文献 | Gonzalez-Cabreraet al (2008) Full pharmacological efficacy of a novel S1P1 agonist that does not require S1P-like headgroup interactions. Mol.Pharmacol. 74 1308. PMID: 18708635. Sannaet al (2006) Enhancement of capillary leakage and restoration of lymphocyte egress by a chiral S1P1antagonistin vivo. Nat.Chem.Biol. 8 434. PMID: 16829954. |