| 货号 | 19355-1mg |
| 描述 | Rhod-2 AM is an acetoxymethyl (AM) ester of the red fluorescent calcium indicator rhod-2. The AM group facilitates cellular uptake and is removed by cytoplasmic esterases, resulting in intracellular accumulation of rhod-2.1,2,3 Rhod-2 AM selectively accumulates within mitochondria and, as a result, is commonly used to monitor calcium changes within this organelle.4,5,6 Excitation and emission maxima are 557 and 581 nm, respectively.3 |
| 别名 | Rhod-2 Acetoxymethyl ester; |
| 供应商 | Cayman |
| 应用文献 | |
| 1.Minta, A.,Kao, J.P., and Tsien, R.Y. Fluorescent indicators for cytosolic calcium based on rhodamine and fluorescein chromophores. The Journal of Biological Chemisty 264(14), 8171-8178 (1989). 2.Jean-Quartier, C.,Bondarenko, A.I.,Alam, M.R., et al. Studying mitochondrial Ca2+ uptake - a revisit. Molecular and Cellular Endocrinology 353(1-2), 114-127 (2012). 3.Paredes, R.M.,Etzler, J.C.,Watts, L.T., et al. Chemical calcium indicators. Methods: A Companion to Methods in Enzymology 46(3), 143-151 (2008). 4.Wang, S.,Chen, J., and Valderrábano, M. Nutrient restriction preserves calcium cycling and mitochondrial function in cardiac myocytes during ischemia and reperfusion. Cell Calcium 51(6), 445-451 (2012). 5.Bodnár, D.,Geyer, N.,Ruzsnavszky, O., et al. Hypermuscular mice with mutation in the myostatin gene display altered calcium signalling. Journal of Physiology 592(6), 1353-1365 (2014). 6.Elamin, E.,Masclee, A.,Troost, F., et al. Cytotoxicity and metabolic stress induced by acetaldehyde in human intestinal LS174T goblet-like cells. American Journal of Physiology and Gastrointestinal Liver Physiology 307(3), G286-G294 (2014). | |
| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥93% |
| 计算分子量 | 1124 |
| 分子式 | C52H59N4O19 • Br |
| CAS号 | 145037-81-6 |
| 稳定性 | ≥ 2 years |
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