货号 | 2138/1 |
供应商 | Tocris |
生物活性 | C-Terminal fragment of xenin, a neurotensin-like peptide; modulates pancreatic insulin and glucagon secretion/effects. Stimulates basal and arginine-induced insulin secretion and potentiates the insulin response to glucose (EC50 = 0.16 nM). Also potentiates arginine- and carbachol-induced glucagon secretion in a somatostatin-independent manner. |
运输条件 | Blue Ice |
存放说明 | -20℃ |
计算分子量 | 1046.28 |
分子式 | C51H79N15O9 |
可溶性/溶解性 | Soluble to 1 mg/ml in water |
CAS号 | 117442-28-1 |
序列号 | HPKRPWIL |
参考文献 | Feurleet al (2003) Metabolism and potency of xenin and of its reduced hexapseudopeptide ψ fragment in dog. Life Sci. 74 697. PMID: 14654163. Silvestreet al (2003) Stimulatory effect of xenin-8 on insulin and glucagon secretion in the perfused rat pancreas. Regul.Pept. 115 25. PMID: 12873795. Carrawayet al (1988) Xenopsin-related peptide generated in avian gastric extracts. Regul.Pept. 22 303. PMID: 2460902. |