| 货号 | 2472/100U |
| 别名 | (2E,4E,7E)-2,4,7-Undecatrienal nitrosohydrazone |
| 供应商 | Tocris |
| 生物活性 | Inhibitor of acyl-CoA synthetase. Inhibits lipid synthesis and cell proliferation in Raji lymphoma cells. Induces apoptosis in cancer cell lines and inhibits human lung cancer cell xenograft tumor growth in mice. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 纯度 | >95 % |
| 计算分子量 | 207.27 |
| 分子式 | C11H17N3O |
| 可溶性/溶解性 | Soluble to 25 mM in DMSO |
| 参考文献 | Mashimaet al (2005) p53-defective tumors with a functional apoptosome-mediated pathway: a new therapeutic target. J.Natl.Cancer.Inst. 97 765. PMID: 15900046. Tomodaet al (1991) Evidence for an essential role of long chain acyl-CoA synthetase in animal cell proliferation. Inhibition of long chain acyl-CoA synthetase by triacsins caused inhibition of Raji cell proliferation. J.Biol.Chem. 266 4214. PMID: 1999415. |