| 货号 | 5304/1 |
| 别名 | 5,11-Dihydroindolo[3,2-b]carbazole- |
| 供应商 | Tocris |
| 生物活性 | High affinity aryl hydrocarbon receptor (AhR) agonist (Kd = 70 p M). Proposed to be an endogenous AhR ligand. Induces transient expression of cytochrome P450-1A1 (CYP1A1) in vitro. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 纯度 | >95 % |
| 计算分子量 | 284.31 |
| 分子式 | C19H12N2O |
| 可溶性/溶解性 | Soluble to 25 mM in DMSO |
| 参考文献 | Moura-Alveset al (2014) AhR sensing of bacterial pigments regulates antibacterial defence. Nature 512 387. PMID: 25119038. Wincentet al (2009) The suggested physiologic aryl hydrocarbon receptor activator and cytochrome P4501 substrate 6-formylindolo[3,2-b]carbazole is present in humans. J.Biol.Chem. 284 2690. PMID: 19054769. Rannuget al (1995) Structure elucidation of two tryptophan-derived, high affinity Ah receptor ligands. Chem.Biol. 2 841. PMID: 8807817. |