CHR 6494 trifluoroacetate (10 MG)
货号:
5326/10 基本售价:
2220.8 元 规格:
10 mg
产品信息
概述货号 | 5326/10 |
别名 | 3-(1H-Indazol-5-yl)-N-propylimidazo[1,2-b]pyridazin-6-amine trifluoroacetate |
性能供应商 | Tocris |
生物活性 | Potent and selective haspin kinase inhibitor (IC50 = 2 nM). Selective over 27 other protein kinases including Aurora B kinase. Induces cell cycle arrest at G2/M, inhibits cell proliferation and promotes apoptosis in multiple cancer cell lines. Inhibits angiogenesis ex vivo and attenuates tumor growth of HCT-116 xenografts in rats. |
运输条件 | Blue Ice |
存放说明 | 4℃ |
纯度 | >98 % |
计算分子量 | 406.36 |
分子式 | C16H16N6.CF3 |
可溶性/溶解性 | Soluble to 100 mM in DMSO |
参考文献 | Huertaset al (2012) Antitumor activity of a small-molecule inhibitor of the histone kinase Haspin. Oncogene 31 1408. PMID: 21804608. |