| 货号 | 2321/1 |
| 别名 | Calcium-like peptide 3 |
| 供应商 | Tocris |
| 生物活性 | Cell-permeable calmodulin (CaM) agonist that binds to the EF-hand/Ca2+-binding site. Activates phosphodiesterase in the absence of Ca2+ and inhibits Ca2+-mediated cytotoxicity and apoptosis (IC50 = 33 μM). |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 计算分子量 | 881.08 |
| 分子式 | C44H68N10O9 |
| 可溶性/溶解性 | Soluble to 1 mg/ml in water |
| CAS号 | 261969-05-5 |
| 序列号 | VKFGVGFK |
| 参考文献 | Ten Broekeet al (2003) Ca2+ sensors modulate asthmatic symptoms in an allergic model for asthma. Eur.J.Pharmacol. 476 151. PMID: 12969760. Manionet al (2000) A new type of Ca2+ channel blocker that targets Ca2+ sensors and prevents Ca2+-mediated apoptosis. FASEB J. 14 1297. PMID: 10877822. Villainet al(2000)De novo design of peptides targeted to the EF hands of calmodulin. J.Biol.Chem. 2742676. |