| 货号 | 2090/1 |
| 别名 | Calcium-like peptide 1 |
| 供应商 | Tocris |
| 生物活性 | Cell-permeable calmodulin (CaM) agonist that binds to the EF-hand/Ca2+-binding site; produces CaM-dependent activation of phosphodiesterase. Also binds to cytoplasmic sites on other Ca2+ channels, including NMDA |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 计算分子量 | 842.09 |
| 分子式 | C40H75N9O10 |
| 可溶性/溶解性 | Soluble to 1 mg/ml in water |
| CAS号 | 145224-99-3 |
| 序列号 | VAITVLVK |
| 参考文献 | Ten Broekeet al (2003) Ca2+ sensors modulate asthmatic symptoms in an allergic model for asthma. Eur.J.Pharmacol. 476 151. PMID: 12969760. Houtmanet al (2001) Attenuation of very late antigen-5-mediated adhesion of bone marrow-derived mast cells to fibronectin by peptides with inverted hydropathy to EF-hands. J.Immunol. 166 861. PMID: 11145661. Manionet al (2000) A new type of Ca2+ channel blocker that targets Ca2+ sensors and prevents Ca2+-mediated apoptosis. FASEB J. 14 1297. PMID: 10877822. Villainet al(2000)De novo design of peptides targeted to the EF hands of calmodulin. J.Biol.Chem. 2742676. |