| 货号 | 16145-25mg |
| 描述 | 20-hydroxy Ecdysone is an ecdysteroid hormone produced in arthropod species that induces developmental changes associated with ecdysis and the completion of metamorphosis.1 It is also produced in plants as a defensive strategy to disrupt the development of insect pests.2 In target tissues, 20-hydroxy ecdysone binds to the nuclear hormone receptor, ecdysone receptor, initiating a signaling cascade that results in cell cycle arrest.1,3 Ecdysteroids such as this compound have been employed as tools in inducible gene regulation systems controlled by reporter cells transfected with the ecdysone receptor.4,5 |
| 别名 | Ecdysterone;Isoinokosterone; |
| 供应商 | Cayman |
| 应用文献 | |
| 1.Fallon, A.M. and Gerenday, A. Ecdysone and the cell cycle: Investigations in a mosquito cell line. J.Insect Physiol. 56(10), 1396-1401 (2010). 2.Boo, K.H.,Lee, D.,Jeon, G.L., et al. Distribution and biosynthesis of 20-hydroxyecdysone in plants of Achyranthes japonica Nakai. Bioscience, Biotechnology, and Biochemistry 74(11), 2226-2231 (2010). 3.Cai, M.J.,Dong, D.J.,Wang, Y., et al. G-protein-coupled receptor participates in 20-hydroxyecdysone signaling on the plasma membrane. Cell Communication and Signaling 12, 11-16 (2014). 4.Saez, E.,Nelson, M.C.,Eshelman, B., et al. Identification of ligands and coligands for the ecdysone-regulated gene switch. Proceedings of the National Academy of Sciences of the United States of America 97(26), 14512-14517 (2000). 5.Karzenowski, D.,Potter, D.W. and Padidam, M. Inducible control of transgene expression with ecdysone receptor: Gene switches with high sensitivity, robust expression, and reduced size. Biotechniques 39(2), 191-192 (2005). | |
| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 480.6 |
| 分子式 | C27H44O7 |
| CAS号 | 5289-74-7 |
| 稳定性 | ≥ 2 years |
| 本官网所有报价均为常温或者蓝冰运输价格，如有产品需要干冰运输，需另外加收干冰运输费。 |