货号 | 1799/1 |
别名 | W-peptide |
供应商 | Tocris |
生物活性 | Selective agonist for the formyl peptide receptors FPR2 and FPR3, expressed on immune cells. EC50 values for induction of calcium mobilization in FPR2-HL-60 cells and FPR3-HL-60 cells are 2 and 80 nM respectively. |
运输条件 | Blue Ice |
存放说明 | -20℃ |
计算分子量 | 856.11 |
分子式 | C41H61N9O7S2 |
可溶性/溶解性 | Soluble to 0.60 mg/ml in water |
CAS号 | 187986-11-4 |
序列号 | WKYMVM (Modifications: Met-6 = C-terminal amide) |
参考文献 | Christopheet al (2002) Phagocyte activation by Trp-Lys-Tyr-Met-Val-Met, acting through FPRL1 /LXA4R, is not affected by lipoxin. Scand.J.Immunol. 56 470. PMID: 12410796. Christopheet al (2001) The synthetic peptide Trp-Lys-Tyr-Met-Val-Met-NH2 specifically activates neutrophils through FPRL1/Lipoxin A4 receptors and is an agonist for the orphan monocyte-expressed chemoattractant receptor FPRL2. J.Biol.Chem. 276 21585. PMID: 11285256. Baeket al (1996) Identification of the peptides that stimulate the phosphoinositide hydrolysis in lymphocyte cell lines from peptide libraries. J.Biol.Chem. 271 8170. PMID: 8626507. |