| 货号 | 1772/100 |
| 别名 | 6-[[3-[4-(2-Methoxyphenyl)-1-pipera |
| 供应商 | Tocris |
| 生物活性 | α1-adrenoceptor antagonist and 5-HT1A receptor agonist (pIC50 values are 6.13 and 6.4 respectively). Clinically used hypotensive agent. |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 纯度 | >99 % |
| 计算分子量 | 423.94 |
| 分子式 | C20H29N5O3.HCl |
| 可溶性/溶解性 | Soluble to 50 mM in water |
| CAS号 | 64887-14-5 |
| 参考文献 | Kolassaet al (1989) Involvement of brain 5-HT1A receptors in the hypotensive response to urapidil. Am.J.Cardiol. 64 7D. PMID: 2569265. van Zwieten PA (1989) Pharmacologic profile of urapidil. Am.J.Cardiol. 64 1D. PMID: 2569262. Grosset al (1987) Urapidil and some analogues with hypotensive properties show high affinities for 5-hydroxytryptamine (5-HT) binding sites of the 5-HT1A subtype and for α1-adrenoceptor binding sites. Naunyn Schmiedebergs Arch.Pharmacol. 336 597. PMID: 2832770. |