| 货号 | 1285/100U |
| 别名 | [9S-(9α,10β,11β,13α)]-2,3,10,11,12,13-H |
| 供应商 | Tocris |
| 生物活性 | Broad spectrum protein kinase inhibitor. Enzymes inhibited include protein kinase C (IC50 = 3 nM), protein kinase A (IC50 = 7 nM), p60v-src tyrosine protein kinase (IC50 = 6 nM) and CaM kinase II (IC50 = 20 nM). |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 纯度 | >98 % |
| 计算分子量 | 466.54 |
| 分子式 | C28H26N4O3 |
| 可溶性/溶解性 | Soluble to 50 mM in DMSO |
| 参考文献 | Yanagiharaet al (1991) Staurosporine: an effective inhibitor for Ca2+/calmodulin-dependent protein kinase II. J.Neurochem. 56 294. PMID: 1846174. Ruegg and Burgess (1989) Staurosporine, K-252 and UCN-01: potent but nonspecific inhibitors of protein kinases. TiPS 10 218. PMID: 2672462. Tamaokiet al (1986) Staurosporine, a potent inhibitor of phospholipid/Ca2+ dependent protein kinase. Biochem.Biophys.Res.Commun. 135 397. PMID: 3457562. |