货号 | 0391/50 |
别名 | N-Acetyl-L-aspartyl-L-glutamic acid; α-NAAG |
供应商 | Tocris |
生物活性 | The most abundant peptide neurotransmitter in the mammalian CNS. A weak activator of NMDA receptors, and a highly selective agonist for mGlu3 receptors. Neuroprotective under non-hydrolysing conditions in vivo. |
运输条件 | Blue Ice |
存放说明 | -20℃ |
纯度 | >96 % |
计算分子量 | 304.26 |
分子式 | C11H16N2O8 |
可溶性/溶解性 | Soluble to 100 mM in water |
CAS号 | 4910-46-7 |
参考文献 | Nealeet al(2000)N-Acetylaspartylglutamate: the most abundant peptide neurotransmitter in the mammalian central nervous system. J.Neurochem. 75 443. PMID: 10899918. Thomaset al(2000)N-Acetylated α-linked acidic dipeptidase converts N-acetylaspartylglutamate from a neuroprotectant to a neurotoxin. J.Pharmacol.Exp.Ther. 295 16. PMID: 10991955. Wroblewskaet al(1997)N-Acetylaspartylglutamate selectively activates mGluR3 receptors in transfected cells. J.Neurochem. 69 174. PMID: 9202308. |