| 货号 | 3010/5 |
| 供应商 | Tocris |
| 生物活性 | Protease-activated receptor 2 (PAR2) agonist (Ki = 9.64 μM and IC50 = 10.4 μM). Corresponds to the tethered ligand exposed by trypsin cleavage of PAR-2. Control peptide VKGILS-NH2 also available (Cat. No. 3392). |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 计算分子量 | 614.78 |
| 分子式 | C28H54N8O7 |
| 可溶性/溶解性 | Soluble to 1 mg/ml in water |
| CAS号 | 190383-13-2 |
| 序列号 | SLIGKV (Modifications: Val-6 = C-terminal amide) |
| 参考文献 | Kankeet al (2005) Binding of a highly potent protease-activated receptor-2 (PAR2) activating peptide, [3H]2-furoyl-LIGRL-NH2, to human PAR2. Br.J.Pharmacol. 145 255. PMID: 15765104. Hollenberg and Compton (2002) International union of pharmacology XXVIII. Proteinase-activated receptors. Pharmacol.Rev. 54 203. PMID: 12037136. Bohmet al (1996) Molecular cloning, expression and potential functions of the human proteinase-activated receptor-2. Biochem.J. 314 1009. PMID: 8615752. |