| 货号 | 3498/10 |
| 供应商 | Tocris |
| 生物活性 | Integrin binding sequence that inhibits integrin receptor function. Decreases systemic inflammation via inhibition of collagen-triggered activation of leukocytes and attenuates expression of inflammatory cytokines, iNOS and MMP-9. Promotes cell attachment and abrogates apoptosis via the mitochondrial pathway in osteoblasts in vitro. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 计算分子量 | 433.42 |
| 分子式 | C15H27N7O8 |
| 可溶性/溶解性 | Soluble to 1 mg/ml in water |
| CAS号 | 91037-65-9 |
| 序列号 | RGDS |
| 参考文献 | Droppelmannet al (2009) Matrix metalloproteinase-2-deficient fibroblasts exhibit an alteration in the fibrotic response to CTGF/CCN2 due to an increase in the levels of endogenous fibronectin. J.Biol.Chem. 284 13551. PMID: 19276073. Moonet al (2009) Synthetic RGDS peptide attenuates lipopolysaccharide-induced pulmonary inflammation by inhibiting integrin signaled MAP kinase pathways. Respir.Res. 10 18. PMID: 19272161. Grigoriouet al (2005) Apoptosis and survival of osteoblast-like cells are regulated by surface attachment. J.Biol.Chem. 280 1733. PMID: 15522882. |