| 货号 | 4683/1 |
| 别名 | Neuropeptide NPVF |
| 供应商 | Tocris |
| 生物活性 | Agonist of the NPFF1 receptor (IC50 = 0.7 nM for inhibition of forskolin-induced cAMP production). Homolog of gonadotropin-inhibitory hormone (GnIH); inhibits activity of gonadotropin-releasing hormone (GnRH) neurons. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 计算分子量 | 969.15 |
| 分子式 | C45H72N14O10 |
| 可溶性/溶解性 | Soluble to 2 mg/ml in 20% acetonitrile / water |
| 序列号 | VPNLPQRF (Phe-8 = C-terminal amide) |
| 参考文献 | Rizwanet al (2012) RFamide-related peptide-3 receptor gene expression in GnRH and kisspeptin neurons and GnRH-dependent mechanism of action. Endocrinology 153 3770. PMID: 22691552. Ubukaet al (2009) Identification of human GnIH homologs, RFRP-1 and RFRP-3, and the cognate receptor, GPR147 in the human hypothalamic pituitary axis. PLoS One 4 e8400. PMID: 20027225. Hinumaet al (2000) New neuropeptides containing carboxy-terminal RFamide and their receptor in mammals. Nat.Cell Biol. 2 703. PMID: 11025660. |