| 货号 | 1466/1 |
| 别名 | [(1aR,1bS,4aR,7aS,7bS,8R,9R,9aS)-9a |
| 供应商 | Tocris |
| 生物活性 | Non-pungent vanilloid TRPV1 (VR1) receptor agonist (Ki = 3.1 μM) that displays non-cooperative binding. Induces apoptosis via a non-VR1 mechanism in Jurkat cells and causes vasoconstriction in vivo. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 纯度 | >98 % |
| 计算分子量 | 688.77 |
| 分子式 | C39H44O11 |
| 可溶性/溶解性 | Soluble in DMSO and in ethanol |
| CAS号 | 175796-50-6 |
| 参考文献 | Griffithset al (2000) Functional and desensitizing effects of the novel synthetic vanilloid-like agent 12-phenylacetate 13-acetate 20-homovanillate (PPAHV) in the perfused rat hindlimb. Br.J.Pharmacol. 131 1408. PMID: 11090114. Machoet al (2000) Phorboid 20-homovanillates induce apoptosis through a VR1-independent mechanism. Chem.Biol. 7 483. PMID: 10903936. Szallasiet al (1996) A novel agonist, phorbol 12-phenylacetate 13-acetate 20-homovanillate, abolishes positive cooperativity of binding by the vanilloid receptor. Eur.J.Pharmacol. 299 221. PMID: 8901026. |