| 货号 | 2967/50 |
| 别名 | (3aS,8aR)-1,2,3,3a,8,8a-Hexahydro-1 |
| 供应商 | Tocris |
| 生物活性 | Physostigmine analog that inhibits acetylcholinesterase. Inhibits production of amyloid precursor protein (APP) and Aβ. Improves morris water maze performance of scopolamine-treated rats. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 纯度 | >98 % |
| 计算分子量 | 337.42 |
| 分子式 | C20H23N3O2 |
| 可溶性/溶解性 | Soluble to 10 mM in DMSO and to 25 mM in ethanol |
| CAS号 | 101246-66-6 |
| 参考文献 | Klein (2007) Phenserine. Expert Opin.Investig.Drugs 16 1087. PMID: 17594192. Utsukiet al (2006) Identification of novel small molecule inhibitors of amyloid precursor protein synthesis as a route to lower Alzheimer's disease amyloid-β peptide. J.Pharmacol.Exp.Ther. 318 855. PMID: 16690718. Janaset al (2005) The cholinesterase inhibitor, phenserine, improves morris water maze performance of scopolamine-treated rats. Life Sci. 76 1073. PMID: 15620572. |