NU 9056 (10 MG)
货号：
4903/10 基本售价：
2072.1 元 规格：
10 mg
产品信息
概述| 货号 | 4903/10 |
| 别名 | 5-(1,2-Thiazol-5-yldisulfanyl)-1,2-thiazole |
性能| 供应商 | Tocris |
| 生物活性 | Selective KAT5 (Tip60) histone acetyltransferase inhibitor (IC50 values are < 2, 60, 36, and >100 μM for KAT5, p300, pCAF and GCN5, respectively). Inhibits protein acetylation in prostate cancer cell lines and blocks DNA damage response. Decreases proliferation of LNCaP cells; induces apoptosis via caspase activation. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 计算分子量 | 232.37 |
| 分子式 | C6H4N2S4 |
| 可溶性/溶解性 | Soluble in DMSO (supplied pre-dissolved in DMSO, 10mg/ml) |
| 参考文献 | Coffeyet al (2012) Characterisation of a Tip60 specific inhibitor, NU9056, in prostate cancer. PLoS One 7 e45539. PMID: 23056207. |
