货号 | 1193/500U |
供应商 | Tocris |
生物活性 | Inhibits Gs and stimulates Gi activity. Inhibits protein kinase C and cAMP-dependent protein kinases. Na+/K+ ATPase inhibitor. |
运输条件 | Blue Ice |
存放说明 | -20℃ |
计算分子量 | 2847 |
分子式 | C131H229N39O |
可溶性/溶解性 | Soluble to 1 mg/ml in water |
序列号 | GIGAVLKVLTTGLPALISWIKRKRQQ (Modifications: Gln-26 = C-terminal amide) |
参考文献 | Fukushimaet al (1998) Melittin, a metabostatic peptide inhibiting Gs activity. Peptides 5 811. PMID: 9663445. Raynoret al (1991) Membrane interactions of amphiphilic polypeptides mastoparan, melittin, plymixin B and cardiotoxin. J.Biol.Chem. 266 2753. PMID: 1847132. Mousliet al (1990) G protein activation: a receptor-independent mode of action for cationic amphiphilic neuropeptides and venom peptides. TiPS 11 358. PMID: 2122563. |