| 货号 | 2566/1 |
| 别名 | MT-II |
| 供应商 | Tocris |
| 生物活性 | High affinity melanocortin receptor agonist (Ki values are 0.67, 6.6, 34 and 46 nM for MC1, MC4, MC3 and MC5 receptors respectively). Stimulates erectile activity, inhibits food intake and displays neuroprotective properties in vivo. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 计算分子量 | 1024.19 |
| 分子式 | C50H69N15O9 |
| 可溶性/溶解性 | Soluble to 1 mg/ml in water |
| CAS号 | 121062-08-6 |
| 序列号 | XDHFRWK (Modifications: X = Nle & N-terminal Ac, Asp-2 = beta-Asp, Phe-4 = D-Phe, Lys-7 = epsilon-Lys, Cyclized = Asp-2 - Lys-7, C-terminal amide) |
| 参考文献 | Ter Laaket al (2003) The potent melanocortin receptor agonist melanotan-II promotes peripheral nerve regeneration and has neuroprotective properties in the rat. Eur.J.Pharmacol. 462 179. PMID: 12591111. Martinet al (2002) Activation of melanocortin MC4 receptors increases erectile activity in rats ex copula. Eur.J.Pharmacol. 454 71. PMID: 12409007. Wikber (1999) Melanocortin receptors: perspectives for novel drugs. Eur.J.Pharmacol. 375395. |