| 货号 | 4799/50 |
| 别名 | 5'-Deoxy-5-fluoro-N-[(pentyloxy)carb |
| 供应商 | Tocris |
| 生物活性 | Prodrug of 5-Fluorouracil (5-FU) (Cat. No. 3257). Selectively activated in tumor cells by thymidine phosphorylase; inhibits DNA synthesis upon conversion to 5-FU. Orally available. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 纯度 | >98 % |
| 计算分子量 | 359.35 |
| 分子式 | C15H22FN3O6< |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO and to 100 mM in ethanol |
| 参考文献 | Desmoulinet al (2002) Metabolism of capecitabine, an oral fluorouracil prodrug: 19F NMR studies in animal models and human urine. Drug Metab.Dispos. 30 1221. PMID: 12386128. Shimmaet al (2000) The design and synthesis of a new tumor-selective fluoropyrimidine carbamate, capecitabine. Bioorg.Med.Chem.Lett. 8 1697. PMID: 10976516. Bhuyanet al (1972) Cell cycle phase specificity of antitumor agents. Cancer Res. 32 398. PMID: 4258018. |