| 货号 | 1333/1 |
| 别名 | (S)-Adenosine, cyclic 3',5'-(hydrogenphosphorothioate) triethylammonium |
| 供应商 | Tocris |
| 生物活性 | Cell-permeable cAMP analog that activates cAMP receptor proteins such as PKA and cAMP-regulated guanine nucleotide exchange factor. Enantiomer cAMPS-Rp, triethylammonium salt (Cat. No. 1337) also available. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 纯度 | >98 % |
| 计算分子量 | 446.46 |
| 分子式 | C10H12N5O5PS.C6H15N |
| 可溶性/溶解性 | Soluble to 100 mM in water |
| CAS号 | 71774-13-5 |
| 参考文献 | Linet al (2006) Ethanol inhibition of NMDA-induced responses and actute tolerance to the inhibition in rat rostral ventrolateral medulla in vivo: Involvement of cAMP-dependent protein kinases. Neuropharmacology 51 747. PMID: 16806304. Kawasakiet al (1998) A family of cAMP-binding proteins that directly activate Rap1. Science 282 2275. PMID: 9856955. Dostmannet al (1990) Probing the cyclic nucleotide binding sites of cAMP-dependent protein kinases I and II with analogs of adenosine 3',5'-cyclic phosphorothioates. J.Biol.Chem. 265 10484. PMID: 2162349. O'Brianet al (1982) A kinetic study of interactions of (Rp)- and (Sp)-adenosine cyclic 3',5'-phosphorothioates with type II bovine cardiac muscle adenosine cyclic 3',5'-phosphate dependent protein kinase. Biochemistry 21 4371. PMID: 6289880. |