货号 | 1870/10 |
别名 | 4-Methyl-N-(phenylmethyl)benzenesul |
供应商 | Tocris |
生物活性 | Selective inhibitor of the ATPase activity of skeletal muscle myosin II subfragment 1 (S1) (IC50 ~ 5 mM). Reversibly blocks gliding motility and suppresses force and twitch production in fast skeletal muscle. |
运输条件 | Blue Ice |
存放说明 | Ambient |
纯度 | >99 % |
计算分子量 | 261.34 |
分子式 | C14H15NO2S |
可溶性/溶解性 | Soluble to 70 mM in ethanol and to 100 mM in DMSO |
CAS号 | 1576-37-0 |
参考文献 | Ramachandranet al (2003) Skeletal muscle myosin cross-bridge cycling is necessary for myofibrillogenesis. Cell Motil.Cytoskeleton 55 61. PMID: 12673599. Shawet al (2003) Mechanism of inhibition of skeletal muscle actomyosin by N-benzyl-p-toluenesulfonamide. Biochemistry 42 6128. PMID: 12755615. Cheunget al (2001) A small-molecule inhibitor of skeletal muscle myosin II. Nat.Cell.Biol. 4 83. PMID: 11744924. |