| 货号 | 2787/25 |
| 别名 | 1,2-Bis(2-aminophenoxy)ethane-N,N,N |
| 供应商 | Tocris |
| 生物活性 | Selective calcium chelator that is the cell-permeable analog of BAPTA (Cat. No. 2786). Blocks hKv1.5, hKV11.1 (hERG) and hKv1.3 channels (Ki values are 1.23, 1.30 and 1.45 μM respectively). Displays antithrombotic activity in vitro. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 纯度 | >95 % |
| 计算分子量 | 764.68 |
| 分子式 | C34H40N2O18 |
| 可溶性/溶解性 | Soluble to 30 mM in DMSO |
| CAS号 | 126150-97-8 |
| 参考文献 | Tanget al (2007) The membrane permeable calcium chelaotr BAPTA-AM directly blocks human ether a-go-go-related gene potassium channels stably expressed in HEK 293 cells. Biochem.Pharmacol. 74 1596. PMID: 17826747. Heilpornet al (1994) Synthesis of BAPTA-AM analogues capable of enhancing the vascuar production of prostacyclin. Bull.Soc.Chim.Belg. 103309. Raspeet al (1989) Enhanced release of prostacyclin from quin 2-loaded endothelial cells. Eur.J.Pharmacol. 163 345. PMID: 2498111. |