货号 | 2756/10 |
别名 | 5Z,8Z,11Z,14Z-Eicosatetraenoic acid |
供应商 | Tocris |
生物活性 | Endogenous free fatty acid released from phospholipids by phospholipase A2, in water-soluble emulsion (for details see TocrisolveTM 100, Cat. No. 1684). Important cellular signaling mediator and precursor of eicosanoids. Metabolized by lipoxygenases, cyclooxygenases and cytochrome P450 monooxygenases. |
运输条件 | Blue Ice |
存放说明 | 4℃ |
计算分子量 | 304.47 |
分子式 | C20H32O2 |
CAS号 | 506-32-1 |
参考文献 | Higuchiet al (2007) Arachidonic acid promotes glutamate-induced cell death associated with necrosis by 12-lipoxygenase activation in glioma cells. Life Sci. 80 1856. PMID: 17400255. Levicket al (2007) Arachidonic acid metabolism as a potential mediator of cardiac fibrosis associated with inflammation. J.Immunol. 178 641. PMID: 17202322. Nakanishiet al (2006) Roles of cPLA2α and arachidonic acid in cancer. Biochim.Biophys.Acta 1761 1335. PMID: 17052951. |