| 货号 | 0281/10 |
| 别名 | (R)-(+)-3-Amino-1-hydroxypyrrolidin |
| 供应商 | Tocris |
| 生物活性 | Antagonist/partial agonist at the glycine site of the NMDA receptor; able to cross the blood-brain barrier. Also available as part of the NMDA Receptor - Glycine Site Tocriset™. S-enantiomer (Cat. No. 0282) available. |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 纯度 | >98 % |
| 计算分子量 | 116.12 |
| 分子式 | C4H8N2O2 |
| 可溶性/溶解性 | Soluble to 100 mM in water |
| CAS号 | 123931-04-4 |
| 参考文献 | Kemp and Priestley (1991) Effects of (+)-HA-966 and 7-chlorokynurenic acid on the kinetics of N-methyl-D-aspartate receptor agonist responses in cat cultured cortical neurons. Mol.Pharmacol. 39 666. PMID: 1674587. Pullanet al (1991) Agonist-like character of the (R) enantiomer of 1-hydroxy-3-amino-pyrrolid-2-one (HA-966). Eur.J.Pharmacol. 208 25. PMID: 1834473. Pullanet al (1990) Stereoselectivity for the (R)-enantiomer of HA-966 (1-hydroxy-3-aminopyrrolidone-2) at the glycine site of the N-methyl-D-aspartate receptor complex. J.Neurochem. 55 1346. PMID: 1975835. |