Dorsomorphin
货号:
1686-5 基本售价:
2049.5 元 规格:
5mg
产品信息
概述货号 | 1686-5 |
描述 | Cell-permeable. A potent, selective , reversible and ATP-competitive inhibitor of AMP-activated protein kinase (AMPK) (Ki = 109 nM in the presence of 5 µM ATP and no AMP). Does not affect the activity on several structurally related kinases including JAK3, PKA, PKCθ, SYK and ZAPK. Also inhibits bone morphogenic protein (BMP) type I receptors (ALK2, ALK3 and ALK6). In addition, recently Dorsomorphin has shown to induce protective autophagy in cancer cells through AMPK inhibition-independent blockade of Akt/mTOR pathway. |
性能供应商 | Biovision |
运输条件 | Blue Ice |
存放说明 | +4℃ |
外观 | Light yellow solid |