| 货号 | 5908/10 |
| 别名 | 4,4'-Bis(phenylamino)-[1,1'-binaphtha |
| 供应商 | Tocris |
| 生物活性 | Fluorescent probe for nonpolar cavities in proteins. Used to detect Aβ fibre (Kd = ~80 nM); exhibits distinct fluorescent profiles for fibres and oligomers. Fluoresces in hydrophobic environments, negligible fluorescence in water solutions. Excitation\emission λ ~ 355\520 nm at pH 7.4. |
| 运输条件 | Ambient |
| 存放说明 | Ambient |
| 纯度 | >97 % |
| 计算分子量 | 672.85 |
| 分子式 | C32H22K2N2 |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO and to 20 mM in water |
| 参考文献 | Younanet al (2015) A comparison of three fluorophores for the detection of amyloid fibers and prefibrillar oligomeric assemblies. ThT (Thioflavin T); ANS (1-Anilinonaphthalene-8-sulfonic Acid); and bisANS (4,4'-Dianilino-1,1'-binaphthyl-5,5'-disulfonic Acid). Biochemistry 54 4297. PMID: 26087242. Rosenet al (1969) Dimer formation from 1-amino-8-naphthalenesulfonate catalyzed by bovine serum albumin. A new fluorescent molecule with exceptional binding properties. Biochemistry 8 3915. PMID: 5388144. |