(±)-Anatoxin A (fumarate)
货号：
14609-1mg 基本售价：
1946.0 元 规格：
1 mg
产品信息
概述| 货号 | 14609-1mg |
| 描述 | (±)-Anatoxin A is a bicyclic amine isolated from the blue-green alga A. aquae that displays high affinity for nicotinic acetylcholine receptors (Kd = 0.1-0.2 μM).1 It binds α4β2- and α7-type nicotinic receptors with Ki values of 1.3 nM and 1.8 μM, respectively, and stimulates [3H]-dopamine release from striatal synaptosomes with an EC50 value of 134 nM.2 |
性能| 供应商 | Cayman |
| 应用文献 |
1.Aronstam, R.S. and Witkop, B. Anatoxin-a interactions with cholinergic synaptic molecules. Proceedings of the National Academy of Sciences of the United States of America 78(7), 4639-4643 (1981).
2.Sharples, C.G.,Kaiser, S.,Soliakov, L., et al. UB-165: A novel nicotinic agonist with subtype selectivity implicates the α4β2 subtype in the modulation of dopamine release from rat striatal synaptosomes. Journal of Neuroscience 20(8), 2783-2791 (2000).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | 4 |
| 纯度 | ≥98% |
| 计算分子量 | 281.3 |
| 分子式 | C10H15NO • C4H4O4 |
| CAS号 | 1219922-30-1 |
| 稳定性 | ≥ 1 year |
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