| 货号 | 3390/100U |
| 供应商 | Tocris |
| 生物活性 | Naturally occuring, potent regulator of actin polymerization present in human platelets at a concentration of 200 - 500 μM. Sequesters G-actin monomers in a 1:1 ratio (Kd = 0.7 - 1.0 μM) and allows rapid filament polymerization in the presence of profilin. Implicated in wound healing, induction of MMPs, chemotaxis, angiogenesis, inflammatory processes and tumor progression. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 计算分子量 | 4963.49 |
| 分子式 | C212H350N56O |
| 可溶性/溶解性 | Soluble to 1 mg/ml in water |
| 序列号 | SDKPDMAEIEKFDKSKLKKTETQEKNPLPS (Modifications: Ser-1 = N-terminal Ac) |
| 参考文献 | Smartet al (2007) Thymosin β4 and angiogenesis: modes of action and therapeutic potential. Angiogenesis 10 229. PMID: 17632766. Huffet al (2001) β-thymosins, small acidic peptides with multiple functions. Int.J.Biochem.Cell Biol. 33 205. PMID: 11311852. Yuet al (1993) Thymosin β10 and thymosin β4 are both actin monomer sequestering proteins. J.Biol.Chem. 268 502. PMID: 8416954. |