| 货号 | 3881/1 |
| 供应商 | Tocris |
| 生物活性 | kisspeptin receptor (KISS1, GPR54) antagonist; kisspeptin-10 (Cat. No. 2570) analog. Inhibits kisspeptin-10 stimulation of inositol phosphate (IP) (IC50 = 7 nM) and release of gonadotrophin-releasing hormone (GnRH). |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 计算分子量 | 1295.42 |
| 分子式 | C63H78N18O13 |
| 可溶性/溶解性 | Soluble to 1 mg/ml in 20% acetonitrile / water |
| CAS号 | 1145998-81-7 |
| 序列号 | Ac-ANWNGFGWRF-NH2 (Modifications: Ala-1 = D-Ala & N-terminal Ac, Trp-8 = D-Trp, Phe-10 = C-terminal amide) |
| 参考文献 | Roseweiret al (2009) Discovery of potent kisspeptin antagonists delineate physiological mechanisms of gonadototrophin regulation. J.Neurosci. 29 3920. PMID: 19321788. |