货号 | 3207/1 |
别名 | (5R,6R,7S,8R,8aS)-Hexahydro-6,7,8-t |
供应商 | Tocris |
生物活性 | Inhibitor of class I α-mannosidases that inhibits glycoprotein processing. Inhibits human endoplasmic reticulum α-1,2-mannosidase I and Golgi Class I mannosidases IA, IB and IC with Ki values of 130 and 23 nM respectively. |
运输条件 | Blue Ice |
存放说明 | -20℃ |
计算分子量 | 232.19 |
分子式 | C8H12N2O6 |
可溶性/溶解性 | Soluble to 10 mM in water with sonication |
CAS号 | 109944-15-2 |
参考文献 | Heringet al (2005) A practical synthesis of kifunensine analogues as inhibitors of endoplasmic reticulum α-Mannosidase I. J.Org.Chem. 70 9892. PMID: 16292820. Elbeinet al (1990) Kifunensine, a potent inhibitor of the glycoprotein processing mannosidase I. J.Biol.Chem. 2651559. |