| 货号 | 1922/5 |
| 供应商 | Tocris |
| 生物活性 | Antagonist at the ghrelin receptor (GHS-R1a) (IC50 = 0.9 μM). Also weakly binds to melanocortin receptors (Ki = 26-120 μM). Centrally active in vivo. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 计算分子量 | 930.12 |
| 分子式 | C49H63N13O6 |
| 可溶性/溶解性 | Soluble to 0.50 mg/ml in water |
| CAS号 | 136054-22-3 |
| 序列号 | HWKWFK (Modifications: Trp-2 = D-Trp, Lys-3 = D-Lys, Phe-5 = D-Phe, Lys-6 = C-terminal amide) |
| 参考文献 | Pinillaet al (2003) Role of ghrelin in the control of growth hormone secretion in prepubertal rats: interactions with excitatory amino acids. Neuroendocrinology 77 83. PMID: 12624529. Traebertet al (2002) Ghrelin acts on leptin-responsive neurones in the rat arcuate nucleus. J.Neuroendocrinol. 14 580. PMID: 12121496. Schiothet al (1997) Characterization of the binding of MSH-B, HP-228, GHRP-6 and 153N-6 to the human melanocortin receptor subtypes. Neuropeptides 31 565. PMID: 9574823. |