| 货号 | 3710/10 |
| 别名 | 2-(Hydroxymethyl)-2-(methoxymethyl) |
| 供应商 | Tocris |
| 生物活性 | Methylated derivative of PRIMA-1 (Cat. No. 1862). Restores mutant activity p53 activity. Acts synergistically with chemotherapeutic agents to inhibit tumor cell proliferation. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 纯度 | >98 % |
| 计算分子量 | 199.25 |
| 分子式 | C10H17NO3 |
| 可溶性/溶解性 | Soluble to 100 mM in water and to 100 mM in DMSO |
| CAS号 | 5291-32-7 |
| 参考文献 | Stuberet al (2009) PRIMA-1MET induces nucleolar translocation of Epstein-Barr virus-encoded EBNA-5 protein. Mol.Cancer 8 23. PMID: 19323829. Shenet al (2008) PRIMA-1MET induces mitochondrial apoptosis through activation of caspase-2. Oncogene 27 6571. PMID: 18663359. Bykovet al (2005) PRIMA-1MET synergizes with cisplatin to induce tumor cell apoptosis. Oncogene 24 3484. PMID: 15735745. |