货号 | 1183/100U |
别名 | Pituitary Adenylate Cyclase-Activating Polypeptide 1-27 |
供应商 | Tocris |
生物活性 | Endogenous neuropeptide showing considerable homology with vasoactive intestinal peptide (VIP). Potently stimulates adenylyl cyclase. |
运输条件 | Blue Ice |
存放说明 | -20℃ |
计算分子量 | 3147.6 |
分子式 | C142H224N40O |
可溶性/溶解性 | Soluble to 1 mg/ml in water |
序列号 | HSDGIFTDSYSRYRKQMAVKKYLAAVL (Modifications: Leu-27 = C-terminal amide) |
参考文献 | Michelet al (1998) XVI. International Union of Pharmacology recommendations for the nomenclature of neuropeptide Y, peptide YY, and pancreatic polypeptide receptors. Pharmacol.Rev. 50 143. PMID: 9549761. Hiroseet al (1997) Pituitary adenylate cyclase-activating polypeptide-27 causes a biphasic chronotropic effect and atrial fibrillation in autonomically decentralized, anaesthetized dogs. J.Pharmacol.Exp.Ther. 283 478. PMID: 9353360. Rawlingset al (1994) Pituitary adenylate cyclase-activating polypeptide increase [Ca2+]i in rat gonadotrophs through an inositol trisphosphate-dependent mechanism. J.Biol.Chem. 269 5680. PMID: 7907085. |