Fura-2 AM
货号：
14591-1mg 基本售价：
1848.0 元 规格：
1 mg
产品信息
概述| 货号 | 14591-1mg |
| 描述 | Fura-2 AM is a noninvasive, intracellular calcium indicator that is UV light-excitable.1 This AM ester form crosses cell membranes and once inside the cell is converted by cellular esterases to fura-2, the pentacarboxylate calcium indicator.2 The spectral properties of fura-2 in the presence of low calcium concentrations (excitation max = 362 nm, emission max = 512 nm) differ from those during high calcium conditions (excitation max = 335 nm, emission max = 505 nm). Measurement of Ca2+-induced fluorescence at excitation wavelengths of both 340 and 380 nm with a constant emission wavelength of 505 nm allows for calculation of calcium concentrations based on a ratio of the 340/380 values. Employing this ratio method cancels out certain variables that could be considered artifacts when attempting to image calcium concentrations in cells. |
| 别名 | Fura-2 Acetoxymethyl ester; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Sabnis, R.W. Handbook of biological dyes and stains: Synthesis and industrial applications. (2010).
2.Grynkiewicz, G.,Poenie, M. and Tsien, R.Y. A new generation of Ca2+ indicators with greatly improved fluorescence properties. The Journal of Biological Chemisty 260(6), 3440-3450 (1985).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥95% |
| 计算分子量 | 1001.9 |
| 分子式 | C44H47N3O24 |
| CAS号 | 108964-32-5 |
| 稳定性 | ≥ 6 months |
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