| 货号 | 5568/10 |
| 别名 | (6R)-6-[[(4-Chlorophenyl)sulfonyl]a |
| 供应商 | Tocris |
| 生物活性 | Potent thromboxane A2 (TP) inhibitor (IC50 = 16.4 nM). Inhibits U 46619 (Cat. No. 1932) induced human platelet aggregation and contraction of isolated rabbit saphenous vein in vitro. Also inhibits U 46619 induced increase in tracheal pressure in guinea pigs. Orally available. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 纯度 | >98 % |
| 计算分子量 | 407.91 |
| 分子式 | C20H22ClNO4S |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO and to 20 mM in ethanol with gentle warming |
| 参考文献 | Wanget al (2014) Potent, long-acting cyclopentane-1,3-Dione thromboxane (A2)-receptor antagonists. ACS Med.Chem.Lett. 5 1015. PMID: 25221659. Cimetièreet al (1998) Synthesis and biological evaluation of new tetrahydronaphthalene derivatives as thromboxane receptor antagonists. Bioorg.Med.Chem.Lett. 8 1375. PMID: 9871769. |