| 货号 | 1068/500U |
| 供应商 | Tocris |
| 生物活性 | NK3 tachykinin receptor agonist. Causes direct excitation of dopamine neurons; enhances dopaminergic function. Induces locomotor activity. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 计算分子量 | 841.97 |
| 分子式 | C40H55N7O11< |
| 可溶性/溶解性 | Soluble to 1 mg/ml in PBS (pH 7.4) |
| 序列号 | DFFGLM (Modifications: Asp-1 = Succinyl-Asp, Phe-3 = Me-Phe, Met-6 = C-terminal amide) |
| 参考文献 | Nordquistet al (2008) The tachykinin NK3 receptor agonist senktide induces locomotor activity in male Mongolian gerbils. Eur.J.Pharmacol. 600 87. PMID: 18930726. Keeganet al (1992) The selective NK receptor agonist senktide excites a subpopulation of dopamine-sensitive neurones in the rat substantia nigra pars compacta in vitro. Br.J.Pharmacol. 105 3. PMID: 1375857. Renzettiet al (1991) Characterization of NK-3 binding sites in rat and guinea-pig cortical membranes by the selective ligand [3H]senktide. Neuropeptides 18 107. PMID: 1712430. |