货号 | 0629/100 |
别名 | 2-(1-Piperazinyl)quinoline dimaleate |
供应商 | Tocris |
生物活性 | Selective 5-HT3 receptor agonist. Also displays antagonist activity at peripheral 5-HT3 receptors. [3H]-Quipazine labels 5-HT3 sites in the cortical membranes. |
运输条件 | Blue Ice |
存放说明 | Ambient |
纯度 | >99 % |
计算分子量 | 445.43 |
分子式 | C13H15N3.2C4H4O4 |
可溶性/溶解性 | Soluble to 100 mM in water |
CAS号 | 5786-68-5 |
参考文献 | Sharifet al (1991) Characteristics of 5-HT3 binding sites in NG108-15, NCB-20 neuroblastoma cells and rat cerebral cortex using [3H]-quipazine and [3H]-GR65630 binding. Br.J.Pharmacol. 102 919. PMID: 1830236. Peroutka and Hamik (1988) [3H]Quipazine labels 5-HT3 recognition sites in rat cortical membranes. Eur.J.Pharmacol. 148 297. PMID: 3378579. Ireland and Tyers (1987) Pharmacological characterization of 5-hydroxytryptamine-induced depolarization of the rat isolated vagus nerve. Br.J.Pharmacol. 90 229. PMID: 3814920. |