货号 | 1460/10 |
别名 | 1,1,1-Trifluoro-2-heptadecanone; Palmityl trifluoromethyl ketone |
供应商 | Tocris |
生物活性 | Phospholipase A2 inhibitor. Can also alter Ca2+ signaling in renal tubular cells. |
运输条件 | Blue Ice |
存放说明 | -20℃ |
纯度 | >99 % |
计算分子量 | 308.43 |
分子式 | C17H31F3O |
可溶性/溶解性 | Soluble to 25 mM in DMSO and to 50 mM in ethanol |
CAS号 | 141022-99-3 |
参考文献 | Janet al (2000) Dual action of palmitoyl trifluoromethyl ketone (PACOCF3) on Ca2+ signaling: activation of extracellular Ca2+ influx and alteration of ATP- and bradykinin-induced Ca2+ responses in Madin Darby canine kidney cells. Arch.Toxicol. 74 447. PMID: 11097381. Lioet al (1996) Irreversible inhibition of Ca2+-independent phospholipase A2 by methyl arachidonyl fluorophosphonate. Biochim.Biophys.Acta 1302 55. PMID: 8695655. Ackermannet al (1995) Inhibition of macrophage Ca2+-independent phospholipase A2 by bromoenol lactone and trifluoromethyl ketones. J.Biol.Chem. 270 445. PMID: 7814408. |