| 货号 | 1702/50 |
| 别名 | N-Cyclopentyladenosine; CPA |
| 供应商 | Tocris |
| 生物活性 | Potent and selective adenosine A1 receptor agonist (Ki values are 2.3, 790 and 43 nM for human A1, A2A and A3 receptors respectively; EC50 = 18600 nM for hA2B). Centrally active following systemic administration in vivo. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 纯度 | >99 % |
| 计算分子量 | 335.36 |
| 分子式 | C15H21N5O4 |
| 可溶性/溶解性 | Soluble to 100 mM in 1eq. HCl |
| CAS号 | 41552-82-3 |
| 参考文献 | Klotz (2000) Adenosine receptors and their ligands. Naunyn Schmiedebergs Arch.Pharmacol. 362 382. PMID: 11111832. Van der Graafet al (1997) Mechanism-based pharmacokinetic-pharmacodynamic modeling of the effects of N6-cyclopentyladenosine analogs on heart rate in rat: estimation of in vivo operational affinity and efficacy at adenosine A1 receptors. J.Pharmacol.Exp.Ther. 283 809. PMID: 9353402. Coffin and Spealman (1987) Behavioral and cardiovascular effects of analogs of adenosine in Cynomolgus monkeys. J.Pharmacol.Exp.Ther. 241 76. PMID: 3572798. |